Research Associate in Bothell, WA

Summary:

• Seeking a highly motivated and enthusiastic Research Associate II who will be part of the Seattle Pilot Facility (SPF) within Client Oncology’s Process Development group.
• Within the SPF, this role will be primarily responsible for supporting the Downstream cell culture operations in our pilot-scale lab (up to 250L) to generate protein materials needed for cross-functional developments as well as GLP toxicology studies.
• This role will be expected to independently execute purification processes from harvest to final fill and to be cross trained in Upstream cell culture processes.
• This is an exciting opportunity to learn the entire monoclonal antibody (mAb) production process, to join a growing & dynamic team, and to significantly contribute to Client Oncology’s mission.

Responsibilities:

• Support protein material generation activities, including both purification and mammalian cell culture operations, from cell thaw to final formulated mAb.
• Escalate equipment or process issues as necessary. Help in troubleshooting and derivation of appropriate corrective action and resolution.
• Prepare buffer and media solutions to support material generation and process development runs.
• Perform equipment (e.g., bioreactor, purification skid, pH meters, and chromatography column, etc.) maintenance.
• Maintain accurate and detailed records of all lab activities and work routinely with electronic data records and applications.
• Generate technical reports and present them in internal meetings.
• Purchase raw materials and consumables.

Qualifications:

• Hands-on experience in purification process and operations, preferably at pilot or manufacturing scales
• Able to follow lab operating procedures and safety guidelines.
• Detail oriented with strong organization and time management skills.
• Team player, motivated and willing to learn and grow.
• Effective written and verbal communication skills.
• Familiarity with lab software and/or electronic lab notebooks (ELN).
• Able to lift and move 50 lbs. repeatedly.
• Weekend and holiday work is required when needed.

Preferred Qualifications:

• Familiar with cell culture experience includes operating both bench-top glass vessel, large-scale single-use bioreactor systems, and associated activities.
• Proficient in lab automation.
• Proficiency with ELN and data management
• Biomanufacturing experience.

Required Skills:

• Large Scale Purification exp (pilot/manufacturing)
• Buffer and Media Prep
• Exp with protein purification 

What is the minimum education experience required:

• Prefer BS
• Associate degree with 2+ years exp

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