Scientist in South San Francisco, CA

Description – External

• The QTAS Department is seeking a highly motivated scientist to support the development and implementation of single cell-based flow cytometric (FCM) assays that enable development of novel therapies from the bench to the clinic.
• The desired candidate will work in a highly collaborative environment to develop pharmacodynamic assays that support internal decision making for preclinical studies and Ph1 clinical trials.
• In this laboratory role, the ideal candidate will perform hands-on assay development and will execute established assays to support candidate therapeutic modalities.
• The work encompasses immunophenotyping in varying matrices and optimizing FCM assays for fit-for-purpose use.
• The ideal candidate will have a strong background in biology, immune-oncology, immunology, molecular biology, biochemistry, or cancer biology and will be supervised by an established subject matter expert.

Key Responsibilities:

• Work as part of a highly collaborative interdisciplinary team in an integrated early drug development laboratory.
• Work with different bioanalytical matrices to support FCM assay development.
• Conduct laboratory experiments to characterize and optimize flow cytometric assays.
• Execute existing pharmacodynamic assays using established SOPs to support early stage immune-oncology and immunology R&D projects in a detail-oriented approach.

Qualifications – External

• Bachelor’s Degree or equivalent education with typically 0-3 years of experience, or Master’s Degree or equivalent education with typically zero - two years of experience
• Experience with mammalian cell culture and/or isolating primary cells.
• Strong communication skills – verbal, written, and scientific data presentation.
• Ability to multitask and highly attentive to detail.
• Ability to learn, understand, and execute new scientific techniques.
• Proficiency with Microsoft Office software, including excel and word; ability to learn new software applications.

Preferred:

• Strongly preference towards candidate with 2+ years of flow cytometry experience; experience with various BD instruments (i.e. Fortessa, Symphony) is highly desirable.
• Experienced with various flow cytometric analysis software including DIVA, FlowJo, FCS express, and GraphPad is highly desirable.

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