Research Associate in Cambridge, MA

Job Title: Research Associate

Location: 100% onsite

Candidates must be able to work, 100% onsite at Cambridge Crossings.
Candidates must be agreeable with the $20/day parking fee at Cambridge Crossings.

Must have list:

• Bachelor's degree in biological sciences, engineering, chemistry, physics, math, computer sciences, or related fields.
• 3+ years of hands on experience in a laboratory.
• Prior experience with spatial technologies or pathology/histology/IHC is preferred but not required.

 Position Summary:

• This position will be part of the Translational Medicine Solid Tumor Lab Research Team based in Cambridge MA, and will focus on tissue-based research, including spatial biology.
• The team deploys the latest high dimensional profiling tools (including single cell genomics/epigenomics and spatial protein/RNA characterization) in patient tumor samples to fill translational knowledge gaps relevant to our early and late development pipelines.
• Such knowledge gaps include the study of tumor and microenvironment heterogeneity, identification of mechanisms of action and resistance to therapy, and improved patient stratification with novel biomarkers.
• This role will support our team to answer key translational questions for our programs. The primary responsibilities of the role will involve performing high dimensional profiling spatial and single cell assays on tissue samples.

Position Responsibilities:

Key responsibilities include operation, maintenance, and troubleshooting of latest generation PhenoCycler Fusion and Nanostring CosMx instrument; preparation of samples and reagents; and assistance in assay development and optimization.

• Operate and maintain the PhenoCycler Fusion and auto-staining instruments.
• Prepare and manage reagents. Perform reagent validation and QC. Prepare slides for analysis.
• Maintain an up-to-date and accurate record of samples, reagents. Maintain and organize the inventory.
• Perform routine data transferring and assist with data analysis.
• Assist in the development of new assays, methods, and reagents.

Qualifications & Experience:

• Bachelor's degree in biological sciences, engineering, chemistry, physics, math, computer sciences, or related fields.
• Prior experience with spatial technologies or pathology/histology/IHC is preferred but not required, as training will be provided.
• Ideal candidates will be quick learners and comfortable with new technologies and have excellent hands-on and organizational skills, with attention to detail and quality.
• Skills for effective and timely communication with colleagues.
• One year of related experience preferred.

Working Conditions:

• Contingent worker will be primarily in a laboratory environment and will work with hazardous materials, including human tissue and blood samples.

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