Assay Development Scientist in San Diego, CA

 Role will be Onsite in San Diego, CA

• Possible titles would be "Assay Development Scientist" or " Oligonucleotides Discovery Scientist"
• Bachelor Degree in Science is required
• Must have exp in Laboratory
• Will support multiple groups including Chemistry group
• Must have Assay experience and knowledge
• Experience with QPCR

(Experience in one or a couple of these areas would be ideal)

• Knowledge with therapies, RNAs
• RNA extractions
• LC/MS experience
• Reviewing concentration readings
• Lipid nanoparticle (LNP) exp
• Oligonucleotides experience
• Electronic Lab notebook exp

Additional Experience:

• Organizational skills
• Help with inventory in the laboratory
• Must have 5 years exp in Labs / technical exp
• Must have MS Office exp

Top Skills:

• Worked in a Laboratory
• Assay Experience
• (A couple skills from the list above that are specific lab skills)

General Summary:

• Responsible for conducting research in assigned areas under direct supervision using established methodology.

 Duties & Responsibilities:

• Plans and conducts moderately complex experiments and analyzes and interprets the results. Keeps accurate records of work undertaken.

Top Three Skills:

• RNA extraction, qPCR, Experience in analytical methods to characterize oligonucleotides.

Support RNA assay development and chemistry by supporting RNA extraction, qPCR, immunoassays, and analytical methods to characterize oligonucleotides

• Conduct and troubleshoot experiments, independently and in collaboration with colleagues, to characterize and screen siRNA oligonucleotides
• Support siRNA characterization by through routine and consistent performance of 4 or more assays
• Support lipid nanoparticle (LNP) development and characterization using dynamic light scattering (DLS), Encapsulation efficiencies (ribogreen fluorescence) and HPLC.
• Support routine tasks associated with siRNA solid phase supported synthesis and characterization using LC/MS.
• Collect and evaluate data; prepare reports, summaries, and presentations; maintain and update laboratory notebook and the laboratory information management system
• Manage inventory of supplies, ordering reagents and consumables

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