Scientist (Surface Plasmon Resonance) in Worcester, MA

Onsite - local preferred

• This person would involving in working with Antibodies and Protein execution
• Will be working with protein, antibody
• Cell culture, Cell binding assays (ELISA or FACS) exp will be considered
• Bachelor with 2-4 years experience or Master’s degree with 1-3 yrs exp
• mass spectrometry (MS) analysis
• Surface Plasmon Resonance (SPR) (MUST have)
• Protein-Protein interactions
• Protein modification and conjugation
• Bachelors with industry exp needed
• Masters or PhD with academic or research exp will work
• Prior ELISA or FACS exp. would be helpful
• Prior flow cytometry exp. would be a plus but not at all a deal breaker

What are the top 3-5 skills, experience or education required for this position?

• Surface Plasmon Resonance (SPR)
• Protein-Protein interactions
• mass spectrometry (MS) analysis
• protein modification and conjugation
• Bachelor with 2-4 years experience or Master’s degree

Biologist II, Biomolecular Interactions & Protein Science Analytics

Client is seeking a highly skilled and self-motivated scientist.

• This role offers the opportunity to make significant contributions to all Discovery Research therapeutic areas and projects by providing analytical and functional characterization of our biopharmaceutical products, including monoclonal antibodies, multi-specifics, and antibody-like biologics.
• The ideal candidate will possess a solid foundation in protein sciences and antibody discovery with a proven ability to work effectively on cross-functional teams. This is an excellent opportunity for a highly motivated scientist to make a meaningful impact in a collaborative and innovative setting.

Key responsibilities:

• Conduct Surface Plasmon Resonance (SPR) assays to generate objective selection criteria for panels of antibodies, multispecifics, and antibody-like biologics.
• Employ various protein characterization techniques such as high-performance liquid chromatography (HPLC) methods, mass spectrometry (MS) analysis, spectroscopy, endotoxin measurements, and other bioanalytical methods to support the protein science workflow.
• Perform diverse protein modification and conjugation methods to facilitate discovery initiatives.
• Implement high-throughput epitope binning of monoclonal antibodies.
• Conduct antibody Fc characterization studies to support regulatory submissions.
• Analyze, document, and report data in a concise manner, ensuring timely delivery.
• Present original work internally across groups as necessary.

Qualifications:

• Bachelor's degree with 2-4 years of relevant experience or a Master's degree in Biochemistry, Biology, or related fields.
• Proven ability to independently execute and interpret experiments.
• Knowledge and hands-on experience with analytical/functional characterization of biologics using SPR, HPLC, MS analysis is preferred.
• Experience with protein-protein interaction analysis is a plus.
• Experience with protein modification and conjugation is a plus.
• Direct experience with biologics, monoclonal antibodies, and/or protein therapeutics is a plus.
• Demonstrated ability to manage multiple tasks efficiently.
• A goal-oriented team player with exceptional verbal and written communication skills, a strong can-do attitude, and the capability to excel in a fast-paced, multidisciplinary environment.

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